Management of mTBI in Children: From Bench to Bedside (Part 1)



Barry Willer


Barry Willer
Kristy Arbogast
Andrew Mayer
Rebekah Mannix
William Meehan



The symposium will be presented in two parts. Part 1 will focus on (a) Prevention, (b) Imaging, (c) Early identification and intervention and (d) Long term consequences of mTBI in children.

Part 1:

(a) Prevention of injury:
Dr. Arbogast will present on the latest findings on paediatric injury biomechanics, injury causation and the effectiveness of safety products. She will focus on children injured in motor vehicle crashes and paediatric concussions. Her research has included the use of head impact sensors as tools in the assessment of concussive forces on children in sports.

(b) Imaging:
Dr. Mayer will describe the most recent imaging research related to mTBI and in particular the impact of injury on the brain’s use of auditory and visual information as demonstrated on functional imaging. Deficits in spatial localization and selective attention are hallmark symptoms that occur in the first weeks of mTBI. Most children recover fully but imaging has provided new insights into those children who do not recover.

(c) Early identification and intervention:
Dr. Mannix is an emergency medicine specialist and will describe the advances in early identification and treatment in the ED. She is especially interested in the use of serum and imaging biomarkers for diagnosing and managing mTBI. She will describe a thoughtful evidence-guided management approach to children with acute concussion.

(d) Long term consequences of mTBI:
Dr. Meehan will describe the most current information on the long-term effects of repeated trauma including the changes in tau deposition that is characteristic of chronic traumatic encephalopathy (CTE). Dr. Meehan’s research using an animal model of CTE has allowed him and his colleagues to look for possible treatments for CTE.



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